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巨臀 董婷 教师

发布日期:2024-10-06 21:48    点击次数:78

巨臀 董婷 教师

巨臀

基本信息:

姓 名: 董婷

出身日历: 1989年12月23日

关联方式: tingdong2021@sdu.edu.cn;18854152103

职责单元: 山东大学药学院

通信地址: 济南市文化西路44号山东大学药学院自然药厌世学征询所

个东说念主简介:

董婷,生厌世学与分子生物学博士,山东大学药学院教师,皆鲁后生学者,博士生导师。主要从事自然产品重编程巨噬细胞用于免疫代谢疾病的机制征询。迄今截至肯求东说念主累计发表学术论文14篇,含第一/共同第一/通信作家论文11篇,其中影响因子10分以上期刊论文7篇(2篇Nature Communications,1篇Journal of the American Chemical Society,2篇Angewandte Chemie International Edition,1篇Pharmacology & Therapeutics,1篇Journal of Advanced Research),参与肯求国际专利2项,得到麻省理工学院博士后资助格式一项(MIT postdoctoral fellowship)。博士后时刻在哈佛大学诺奖得主E. J. Corey教师推行室作念短期化学生物学照顾人。现在是国际学术期刊《Natural Products and Bioprospecting》、《Annals of Community Medicine and Primary Health Care》、IUBMB Life的编委,并担任多个SCI期刊的审稿东说念主,包括PeerJ, Heliyon, Biomedicine & Phamacotherapy, Bone Research以及Internaltionl Journal of Oral Science。

莳植配景:

2011-09 至 2016-06,  巨臀北京协和医学院, 生厌世学与分子生物学 , 博士

2007-09 至 2011-06,  西北农林科技大学, 愚弄化学, 学士

征询履历:

2021 于今,  山东大学, 药学院, 教师

2017 至 2021,  麻省理工学院,博士后

2016 至 2017,  哈佛医学院,哈佛大学干细胞与组织再生生物学系以及丹娜法伯癌症征询所,博士后

征询看法:

1. mRNA体内可视化器用的建树以及愚弄

2.免疫重编程抗软弱机制征询

承担课题:

1. 山东省国外优青,自然药厌世学(No. 2022HWYQ-033),60万,2022.04-2025.03(在研)

2. 国度当然科学基金-后生格式,GPR3/β-arrestin2信号轴代谢重编程巨噬细胞的机制征询(No. 82204404),30万,2023.01-2025.12(在研)

代表性著述:

Huirui Wang, Yinghui Gao, Li Wang, Yang Yu, Jiaozhen Zhang, Chunyu Liu, Yaxin Song, Haochuan Xu, Jingcheng Wang, Hongxiang Lou*, Ting Dong*(通信). Lung specific homing of diphenyleneiodonium chloride improves pulmonary fibrosis by inhibiting macrophage M2 metabolic program. Journal of Advanced Research. 2022. https://doi.org/10.1016/j.jare.2022.04.012

Ting Dong#, Xinyi Chen#, Haochuan Xu, Yaxin Song, Huirui Wang, Yinghui Gao, Jingcheng Wang, Ruiqing Du, Hongxiang Lou*, Ting Dong*(通信). Mitochondrial metabolism mediated macrophage polarization in chronic lung diseases. Pharmacology & Therapeutics, 2022 Nov; 239: 108208.

Yingzhong Li#, Nikola A Ivica#, Ting Dong#(共一), Dimitrios P Papageorgiou, Yanpu He, Douglas R Brown, Marianna Kleyman, Guangan Hu, Walter W Chen, Lucas B Sullivan, Amanda Del Rosario, Paula T Hammond, Matthew G Vander Heiden, Jianzhu Chen. MFSD7C switches mitochondrial ATP synthesis to thermogenesis in response to heme. Nature. Communications, 2020, 11, 4837.

Guangan Hu*, Ting Dong, Sisi Wang, Hongyu Jing, and Jianzhu Chen*. Vitamin D3-Vitamin D receptor axis suppresses pulmonary emphysema by maintaining alveolar macrophage homeostasis and function. EBioMedicine, 2019, 45, 563-577.

Xiaohui Liu#, Ting Dong#(共一), Yu Zhou, Niu Huang and Xiaoguang Lei*. Exploring the Binding Proteins of Glycolipids with Bifunctional Chemical Probes. Angewandte Chemie International Edition, 2016, 55, 14330.

Ting Dong#(共一), Chao Li#, Xing Wang, Longyang Dian, Xiuguo Zhang, Lin Li, She Chen, Ran Cao, Li Li, Niu Huang, Sudan He* & Xiaoguang Lei*. Ainsliadimer A selectively inhibits IKKα/β by covalently binding a conserved cysteine. Nature Communications, 2015, 6, 6522.

Ting Dong, Weilong Liu, Zhirong Shen, Lin Li, She Chen & Xiaoguang Lei*. Pterisolic Acid B is a Nrf2 Activator by Targeting C171 within Keap1-BTB Domain. Scientific Reports, 2016, 6, 19231.

Ting Dong, Liao Daohong, Liu Xiaohui & Xiaoguang Lei*. Using Small Molecules to Dissect Non-apoptotic Programmed Cell Death: Necroptosis, Ferroptosis, and Pyroptosis. ChemBioChem 2015, 16, 2557.

Zhang Xiaoyun#, Dong Ting#(共一), Li Qiang, Xiaohui Liu, Xiaoying Yang & Xiaoguang Lei*. Second Generation TQ-Ligation for Cell Organelle Imaging. ACS Chemical Biology, 2015, 10, 1676.

Chao Li#, Ting Dong#(共一), Qiang Li & Xiaoguang Lei*. Probing the Anti-cancer Mechanism of (-)-Ainsliatrimer A through Diverted Total Synthesis and Bioorthogonal Ligation. Angewandte Chemie International Edition, 2014. 53, 12111.

黑丝捆绑

Qiang Li#, Ting Dong#(共一), Xiaohui Liu & Xiaoguang Lei*. A Bioorthogonal Ligation Enabled by Click Cycloaddition of o‑Quinolinone Quinone Methide and Vinyl Thioether. Journal of the American Chemical Society, 2013, 135, 4996. (News story describing this work was highlighted in Chem. & Eng. News. 2013, 14, 37.)

Qiang Li, Ting Dong, Xiaohui Liu, Xiaoyun Zhang & Xiaoguang Lei*. ortho-Quinolinone Quinone Methide Finds its Applications in the Bioorthogonal Ligation. Current Organic Chemistry, 2014, 18, 86.

Chao Li, Ting Dong, Longyang Dian, Weidong Zhang & Xiaoguang Lei*. Biomimetic syntheses and structural elucidation of the apoptosis-inducing sesquiterpenoid trimers:(-)ainsliatrimers A and B. Chemical Science, 2013, 4, 1163.

专利:

Xiaoguang Lei, Chao Li, Ting Dong. Sesquiterpenoids, US patent, 20170044180, 02-06-2017.

Chen Jianzhu,Nikola,Li Yingzhong,Dong Ting. TARGET FOR MODULAT ING BODY MASS, US patent, WO 2022/051254 A2,10-03-2021.

会斟酌说:

特邀论说《2ND International Conference on Microbiology & Infectious Diseases》(2022)

麻省理工学术年会 (2019)

麻省理工学术年会 (2018)

 



 




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